Recent advances in 3D-printing-based organ-on-a-chip

Recent advances in 3D-printing-based organ-on-a-chip

Blog Article

Organ-on-a-chip (OOC) facilitates precise manipulation of fluids in microfluidic chips and simulation of the physiological, chemical, and mechanical characteristics of tissues, thus providing a promising tool for in vitro drug screening and physiological modeling.In recent decades, this technology has advanced rapidly because of the development of various three-dimensional (3D) printing techniques.3D printing can not only fabricate microfluidic chips using materials such as resins and polydimethylsiloxane but also construct biomimetic tissues Industrial using bioinks such as cell-loaded hydrogels.In this review, recent advances in 3D-printing-based OOC are systematically summarized based on materials used for direct or indirect 3D printing of OOC, 3D printing techniques for the construction of OOC, and applications of 3D-printing-based OOC in models of the heart, blood vessels, intestines, liver, and kidney.

Moreover, the paper outlines 27" Built-In Microwave/Oven prospective vistas and hurdles within the field, intended to catalyze innovative use of 3D printing methodologies to propel OOC advancements.